KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC7
All Species:
25.76
Human Site:
T446
Identified Species:
62.96
UniProt:
Q8N3Z6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3Z6
NP_115602.2
543
63052
T446
W
P
Q
E
N
K
E
T
Q
K
E
M
K
N
K
Chimpanzee
Pan troglodytes
XP_001169534
543
63034
T446
W
P
Q
E
N
K
E
T
Q
K
E
M
K
N
K
Rhesus Macaque
Macaca mulatta
XP_001114863
543
63168
T446
W
P
Q
E
N
K
E
T
Q
K
E
M
K
N
K
Dog
Lupus familis
XP_538733
544
63251
T446
W
P
Q
E
K
K
E
T
Q
K
E
M
S
R
S
Cat
Felis silvestris
Mouse
Mus musculus
B1AX39
541
62982
T442
W
P
R
E
N
K
E
T
Q
K
E
K
T
R
S
Rat
Rattus norvegicus
B1WC15
542
63308
T443
W
P
R
E
S
K
E
T
Q
K
E
K
T
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509565
566
65060
S462
W
P
R
G
E
R
Y
S
T
K
A
K
S
Q
D
Chicken
Gallus gallus
XP_424418
619
69362
S533
Q
R
A
K
K
H
R
S
D
V
E
R
G
H
E
Frog
Xenopus laevis
A1L2T6
563
64391
K479
C
A
E
T
K
Q
K
K
K
H
K
K
R
K
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199064
921
104738
S590
F
I
E
K
D
Q
T
S
K
K
K
V
L
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.3
73.5
N.A.
64.8
64.8
N.A.
54.5
36.5
40.5
N.A.
N.A.
N.A.
N.A.
N.A.
22.1
Protein Similarity:
100
99.6
97.6
82.1
N.A.
77.1
76.9
N.A.
69.7
52
56.1
N.A.
N.A.
N.A.
N.A.
N.A.
34.6
P-Site Identity:
100
100
100
73.3
N.A.
66.6
60
N.A.
20
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
73.3
N.A.
73.3
73.3
N.A.
40
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% D
% Glu:
0
0
20
60
10
0
60
0
0
0
70
0
0
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
10
0
0
0
10
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
20
30
60
10
10
20
80
20
40
30
10
30
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
0
% M
% Asn:
0
0
0
0
40
0
0
0
0
0
0
0
0
40
0
% N
% Pro:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
10
0
40
0
0
20
0
0
60
0
0
0
0
10
0
% Q
% Arg:
0
10
30
0
0
10
10
0
0
0
0
10
10
30
0
% R
% Ser:
0
0
0
0
10
0
0
30
0
0
0
0
20
0
30
% S
% Thr:
0
0
0
10
0
0
10
60
10
0
0
0
20
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% V
% Trp:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _